Publications & Awards

Selected Publications

Mayer JU, Hilligan KL, Chandler JS, Eccles DA, Old SI, Domingues RG, Yang J, Webb GR, Munoz-Erazo L, Hyde EJ, Wakelin KA, Tang SC, Chappell SC, von Daake S, Brombacher F, Mackay CR, Sher A, Tussiwand R, Connor LM, Ortega DG, Jankovic D, Gros GL, Hepworth MR, Lamiable O, Ronchese F. (2021) Homeostatic IL-13 in healthy skin directs dendritic cell differentiation to promote TH2 and inhibit TH17 cell polarization. Nat. Immunol., 1 (13). https://doi.org/10.1038/s41590-021-01067-0.

Ferrer-Font L, Mehta P, Harmos P, Schmidt AJ, Chappell S, Price KM, Hermans IF, Ronchese F, le Gros G, Mayer JU. (2020) High-Dimensional Analysis of Intestinal Immune Cells during Helminth Infection. eLife, 9, e51678. https://doi.org/10.7554/eLife.51678.


2024

Ferrer-Font F, Burn OK, Mayer JU, Price KM. (2024) Immunophenotyping challenging tissue types using high-dimensional full spectrum flow cytometry. Meth Cell Biol. 0091-679X. https://doi.org/10.1016/bs.mcb.2024.02.014

2023

Schülke S, Gilles S, Jirmo AC, Mayer JU. (2023) Tissue-specific antigen-presenting cells contribute to distinct phenotypes of allergy. Eur. J. Immunol. 0:2249980. https://doi.org/10.1002/eji.202249980

Schinner J, Cunha T, Mayer JU, Hörster S, Kind P, Didona D, Keber C, Hertl M, Worzfeld T and Juratli HA. (2023) Skin-infiltrating T cells display distinct inflammatory signatures in lichen planus, bullous pemphigoid and pemphigus vulgaris. Front. Immunol. 14:1203776. https://doi.org/10.3389/fimmu.2023.1203776

Möbs C, Salheiser M, Bleise F, Witt M, Mayer JU. (2023) Basophils control T cell priming through soluble mediators rather than antigen presentation. Front. Immunol. 13:1032379. https://doi.org/ 10.3389/fimmu.2022.1032379


2022

Pleuger C, Ai D, Hoppe ML, Winter LT, Bohnert D, Karl D, Guenther S, Epelman S, Kantores C, Fijak M, Ravens S, Middendorff R, Mayer JU, Loveland KL, Hedger M, Bhushan S, Meinhardt A. (2022) The regional distribution of resident immune cells shapes distinct immunological environments along the murine epididymis. eLife, 11:e82193. https://doi.org/10.7554/eLife.82193

Prasit, KK, Ferrer-Font L, Burn OK, Anderson RJ, Compton BJ, Schmidt AJ, Mayer JU, Chen CJ, Dasyam N, Ritchie DS, Godfrey DI, Mattarollo SR, Dunbar PR, Painter GF, Hermans IF. (2022) Intratumoural administration of an NKT cell agonist with CpG promotes NKT cell infiltration associated with an enhanced antitumour response and abscopal effect. OncoImmunology, 11(1):2081009. https://doi.org/10.1080/2162402X.2022.2081009

Albrecht M, Schaub B, Gilles S, Köhl J, Altrichter S, Voehringer D, Spillner E, Ehlers M, Jönsson F, Loser K, Mayer JU, Rösner LM, Möbs C, Heine G, Pfützner W. (2022) Current research and unmet needs in allergy and immunology in Germany: report presented by the DGfI and DGAKI task force Allergy & Immunology. Eur. J. Immunol., 52(6):851-855. https://doi.org/10.1002/eji.202270065


2021

Mayer JU, Hilligan KL, Chandler JS, Eccles DA, Old SI, Domingues RG, Yang J, Webb GR, Munoz-Erazo L, Hyde EJ, Wakelin KA, Tang SC, Chappell SC, von Daake S, Brombacher F, Mackay CR, Sher A, Tussiwand R, Connor LM, Ortega DG, Jankovic D, Gros GL, Hepworth MR, Lamiable O, Ronchese F. (2021) Homeostatic IL-13 in healthy skin directs dendritic cell differentiation to promote TH2 and inhibit TH17 cell polarization. Nat. Immunol., 1 (13). https://doi.org/10.1038/s41590-021-01067-0

Naidoo K, Woods K, Pellefigues C, Cait A, O’Sullivan D, Gell K, Marshall AJ, Anderson RJ, Li Y, Schmidt A, Prasit K, Mayer JU, Gestin A, Hermans IF, Painter G, Jacobsen EA, Gasser O. (2021) MR1-Dependent Immune Surveillance of the Skin Contributes to Pathogenesis and Is a Photobiological Target of UV Light Therapy in a Mouse Model of Atopic Dermatitis. Allergy, 76 (10), 3155–3170. https://doi.org/10.1111/all.14994

Sheng J, Chen Q, Wu X, Dong YW, Mayer J, Zhang J, Wang L, Bai X, Liang T, Sung YH, Goh WWB, Ronchese F, Ruedl C. (2021) Fate Mapping Analysis Reveals a Novel Murine Dermal Migratory Langerhans-like Cell Population. eLife, 10, e65412. https://doi.org/10.7554/eLife.65412

Kästele V, Mayer J, Lee ES, Papazian N, Cole JJ, Cerovic V, Belz G, Tomura M, Eberl G, Goodyear C, Maciewicz RA, Wall D, Cupedo T, Withers DR, Milling S. (2021) Intestinal-Derived ILCs Migrating in Lymph Increase IFNγ Production in Response to Salmonella Typhimurium Infection. Mucosal Immunol., 14 (3), 717–727. https://doi.org/10.1038/s41385-020-00366-3

2020

Lamiable O, Mayer JU, Munoz-Erazo L, Ronchese F. (2020) Dendritic Cells in Th2 Immune Responses and Allergic Sensitization. Immunol. Cell Biol., 98 (10), 807–818. https://doi.org/10.1111/imcb.12387

Ronchese F, Hilligan KL, Mayer JU. (2020) Dendritic Cells and the Skin Environment. Curr. Opin. Immunol., 64, 56–62. https://doi.org/10.1016/j.coi.2020.03.006

Mayer JU, Brown SL, MacDonald AS, Milling SW. (2020) Defined Intestinal Regions Are Drained by Specific Lymph Nodes That Mount Distinct Th1 and Th2 Responses Against Schistosoma Mansoni Eggs. Front. Immunol., 11 (2745). https://doi.org/10.3389/fimmu.2020.592325 (corresponding author)

Hilligan KL, Tang SC, Hyde EJ, Roussel E, Mayer JU, Yang J, Wakelin KA, Schmidt AJ, Connor LM, Sher A, MacDonald AS, Ronchese F. (2020) Dermal IRF4+ Dendritic Cells and Monocytes License CD4+ T Helper Cells to Distinct Cytokine Profiles. Nat. Commun., 11 (1), 5637. https://doi.org/10.1038/s41467-020-19463-9

You H, Mayer JU, Johnston RL, Sivakumaran H, Ranasinghe S, Rivera V, Kondrashova O, Koufariotis, LT, Du X, Driguez P, French JD, Waddell N, Duke MG, Ittiprasert W, Mann VH, Brindley PJ, Jones MK, McManus DP. (2020) CRISPR/Cas9-Mediated Genome Editing of Schistosoma Mansoni Acetylcholinesterase. FASEB J., 35 (1), e21205. https://doi.org/10.1096/fj.202001745RR

Bosteels C, Neyt K, Vanheerswynghels M, van Helden MJ, Sichien D, Debeuf N, De Prijck S, Bosteels V, Vandamme N, Martens L, Saeys Y, Louagie E, Lesage M, Williams DL, Tang SC, Mayer JU, Ronchese F, Scott CL, Hammad H, Guilliams M, Lambrecht BN. (2020) Inflammatory Type 2 CDCs Acquire Features of CDC1s and Macrophages to Orchestrate Immunity to Respiratory Virus Infection. Immunity, 52 (6), 1039-1056 e9. https://doi.org/10.1016/j.immuni.2020.04.005

Ferrer-Font L, Mayer JU, Old S, Hermans IF, Irish J, Price KM. (2020) High-Dimensional Data Analysis Algorithms Yield Comparable Results for Mass Cytometry and Spectral Flow Cytometry Data. Cytom. Part A, J. Int. Soc. Anal. Cytol., 97 (8), 824–831. https://doi.org/10.1002/cyto.a.24016 (joint first author)

Giladi A, Cohen M, Medaglia C, Baran Y, Li B, Zada M, Bost P, Blecher-Gonen R, Salame TM, Mayer JU, David E, Ronchese F, Tanay A, Amit I. (2020) Dissecting Cellular Crosstalk by Sequencing Physically Interacting Cells. Nat. Biotechnol., 38 (5), 629–637. https://doi.org/10.1038/s41587-020-0442-2

Ferrer-Font L, Pellefigues C, Mayer JU, Small SJ, Jaimes MC, Price KM. Panel Design and Optimization for High-Dimensional Immunophenotyping Assays Using Spectral Flow Cytometry. (2020) Curr. Protoc. Cytom., 92 (1), e70. https://doi.org/10.1002/cpcy.70

Ferrer-Font L, Mehta P, Harmos P, Schmidt AJ, Chappell S, Price KM, Hermans IF, Ronchese F, le Gros G, Mayer JU. (2020) High-Dimensional Analysis of Intestinal Immune Cells during Helminth Infection. eLife, 9, e51678. https://doi.org/10.7554/eLife.51678


2019 and earlier

Mayer JU. (2019) Commentary: Spatiotemporal Modeling of the Key Migratory Events During the Initiation of Adaptive Immunity. Front. Immunol., 10, 2311. https://doi.org/10.3389/fimmu.2019.02311

Schmidt AJ, Mayer JU, Wallace PK, Ronchese F, Price KM. (2019) Simultaneous Polychromatic Immunofluorescent Staining of Tissue Sections and Consecutive Imaging of up to Seven Parameters by Standard Confocal Microscopy. Curr. Protoc. Cytom., 91 (1), e64. https://doi.org/10.1002/cpcy.64 (joint first author)

Blecher-Gonen R, Bost P, Hilligan KL, David E, Salame TM, Roussel E, Connor LM, Mayer JU, Bahar Halpern K, Toth B, Itzkovitz S, Schwikowski B, Ronchese F, Amit I. (2019) Single-Cell Analysis of Diverse Pathogen Responses Defines a Molecular Roadmap for Generating Antigen-Specific Immunity. Cell Syst., 8 (2), 109-121 e6. https://doi.org/10.1016/j.cels.2019.01.001

Mayer JU, Demiri M, Agace WW, MacDonald AS, Svensson-Frej M, Milling SW. (2017) Different Populations of CD11b(+) Dendritic Cells Drive Th2 Responses in the Small Intestine and Colon. Nat. Commun., 8, 15820. https://doi.org/10.1038/ncomms15820

Schridde A, Bain CC, Mayer JU, Montgomery J, Pollet E, Denecke B, Milling SWF, Jenkins SJ, Dalod M, Henri S, Malissen B, Pabst O, Mowat A. (2017) Tissue-Specific Differentiation of Colonic Macrophages Requires TGFbeta Receptor-Mediated Signaling. Mucosal Immunol., 10 (6), 1387–1399. https://doi.org/10.1038/mi.2016.142

Awards and Recognitions

2024

2023

2022

2021

2020 and earlier